Obesity and disease tied to dramatic dietary changes

The 'mismatch hypothesis' argues that our bodies evolved to digest the foods that our ancestors ate, and that human bodies will struggle and largely fail to metabolize a radically new set of foods. This intuitive idea is hard to test directly, but the Turkana, a pastoralist population in remote Kenya, present a natural experiment: genetically homogenous populations whose diets stretch across a lifestyle gradient from relatively 'matched' to extremely 'mismatched' with their recent evolutionary h...